Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11073531 | 0.87 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1MEN1MAPTHPGD | |
| SCHEMBL7453212 | 0.81 | CYP19A1 (0.37) | MAOBACHEALDH1A1L3MBTL1MAPT | |
| SCHEMBL9850351 | 0.81 | ALDH1A1 (0.41) | MAOBALDH1A1L3MBTL1MEN1MAPT | |
| SCHEMBL11073520 | 0.80 | ALDH1A1 (0.40) | MAOBALDH1A1L3MBTL1MEN1MAPT | |
| SCHEMBL29055300 | 0.80 | ALDH1A1 (0.40) | MAOBALDH1A1L3MBTL1MEN1MAPT | |
| SCHEMBL11062345 | 0.79 | ATM (0.47) | MAOBALDH1A1L3MBTL1MAPTHPGD | |
| SCHEMBL10689675 | 0.78 | ALDH1A1 (0.39) | MAOBALDH1A1L3MBTL1MEN1MAPT | |
| SCHEMBL338454 | 0.78 | ALDH1A1 (0.41) | MAOBALDH1A1L3MBTL1MEN1MAPT | |
| SCHEMBL1653589 | 0.78 | ALDH1A1 (0.41) | MAOBALDH1A1L3MBTL1MEN1MAPT | |
| SCHEMBL11073178 | 0.78 | CA2 (0.43) | ALDH1A1L3MBTL1MAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4595768-A | 3-(substituted phenyl)phthalides | THE HILTON-DAVIS CHEMICAL CO. (US) | 1986-06-17 | — | — | US | claimed |
| US-4732991-A | Substituted phthalides | HILTON DAVIS CHEMICAL CO. (US) | 1988-03-22 | — | — | US | disclosed |
| US-4595768-A | 3-(substituted phenyl)phthalides | THE HILTON-DAVIS CHEMICAL CO. (US) | 1986-06-17 | — | — | US | disclosed |