Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 10/20 | 0.70 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10689449 | 0.82 | ALOX5 (1.00) | ALOX5PTGS1PTGS2L3MBTL1NR4A1 | |
| SCHEMBL4166459 | 0.82 | P4HTM (0.63) | ALOX5PTGS1PTGS2P4HTMNR4A1 | |
| SCHEMBL30697582 | 0.78 | PRMT5 (0.60) | ALOX5P4HTML3MBTL1 | |
| SCHEMBL3944540 | 0.77 | P4HTM (0.57) | ALOX5PTGS1PTGS2P4HTML3MBTL1 | |
| SCHEMBL10695830 | 0.75 | ALOX5 (0.74) | ALOX5PTGS1PTGS2L3MBTL1LTB4R | |
| SCHEMBL4170920 | 0.74 | P4HTM (0.53) | ALOX5PTGS1PTGS2P4HTMNR4A1 | |
| SCHEMBL226721 | 0.74 | P4HTM (0.59) | ALOX5PTGS1PTGS2P4HTML3MBTL1 | |
| SCHEMBL2053753 | 0.74 | FFAR1 (0.67) | P4HTMNR4A1NR4A2NR4A3 | |
| SCHEMBL5261959 | 0.74 | P4HTM (0.55) | ALOX5PTGS1PTGS2P4HTML3MBTL1 | |
| SCHEMBL1974876 | 0.73 | P4HTM (0.58) | ALOX5PTGS1PTGS2P4HTML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0196674-A2 | Hydroxamates as modulators of arachidonic acid metabolic pathways | USV PHARMACEUTICAL CORPORATION (US) | 1986-10-08 | — | — | EP | claimed |
| US-4792560-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1988-12-20 | — | — | US | disclosed |