Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 13/20 | 0.74 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.53 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10689449 | 0.86 | ALOX5 (1.00) | ALOX5PTGS1PTGS2LTB4RLTB4R2 | |
| SCHEMBL10693993 | 0.78 | ALOX5 (1.00) | ALOX5PTGS1PTGS2LTB4RLTB4R2 | |
| SCHEMBL2755055 | 0.77 | ALOX5 (1.00) | ALOX5PTGS1PTGS2LTB4RLTB4R2 | |
| SCHEMBL10692791 | 0.77 | ALOX5 (1.00) | ALOX5PTGS1PTGS2LTB4RLTB4R2 | |
| SCHEMBL4013173 | 0.76 | PARP10 (0.62) | ALOX5KDM4EALDH1A1MAOB | |
| SCHEMBL10692771 | 0.76 | ALOX5 (1.00) | ALOX5PTGS1PTGS2LTB4RLTB4R2 | |
| SCHEMBL10692328 | 0.75 | ALOX5 (0.70) | ALOX5PTGS1PTGS2LTB4RLTB4R2 | |
| SCHEMBL3132030 | 0.74 | ALOX5 (0.83) | ALOX5PTGS1PTGS2LTB4RLTB4R2 | |
| SCHEMBL23637666 | 0.74 | L3MBTL1 (0.56) | PTGS1PTGS2KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL6176980 | 0.74 | ALOX5 (0.56) | ALOX5PTGS1PTGS2LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792560-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0196674-A2 | Hydroxamates as modulators of arachidonic acid metabolic pathways | USV PHARMACEUTICAL CORPORATION (US) | 1986-10-08 | — | — | EP | disclosed |