Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GRM6 | O15303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7000927 | 0.79 | GRM6 (0.45) | CYP1A2CYP2C19CYP2A6TSHRALDH1A1 | |
| SCHEMBL27386975 | 0.77 | CYP1A2 (0.36) | CYP1A2CYP2C19CYP2A6TSHRALDH1A1 | |
| SCHEMBL10692731 | 0.77 | KDM4E (0.32) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL16273147 | 0.71 | TSHR (0.50) | CYP1A2CYP2C19CYP2A6TSHRALDH1A1 | |
| SCHEMBL1514430 | 0.71 | GPR3 (0.44) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL142551 | 0.70 | CYP1A2 (0.55) | CYP1A2CYP2A6TSHRALDH1A1MAPT | |
| SCHEMBL29364650 | 0.70 | CYP1A2 (0.55) | CYP1A2CYP2A6TSHRALDH1A1MAPT | |
| SCHEMBL16442543 | 0.68 | ALDH1A1 (0.44) | CYP1A2CYP2A6TSHRALDH1A1 | |
| Hydrogen Sulfide SCHEMBL28590036 | 0.68 | CYP1A2 (0.52) | CYP1A2CYP2A6TSHRALDH1A1MAPT | |
| SCHEMBL18347527 | 0.68 | TSHR (0.46) | CYP1A2CYP2A6TSHRALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4737516-A | FUNGICIDES | SANDOZ LTD. (CH) | 1988-04-12 | — | — | US | disclosed |