Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 8/20 | 0.62 |
| ▸ | HTR2C | P28335 | 8/20 | 0.62 |
| ▸ | HTR2B | P41595 | 7/20 | 0.62 |
| ▸ | DRD1 | P21728 | 6/20 | 0.52 |
| ▸ | DRD5 | P21918 | 4/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11452002 | 0.92 | DRD1 (0.57) | HTR2AHTR2CHTR2BDRD1DRD5 | |
| SCHEMBL11103719 | 0.84 | DRD1 (0.70) | HTR2AHTR2CHTR2BDRD1DRD5 | |
| SCHEMBL11103721 | 0.84 | DRD1 (0.70) | HTR2AHTR2CHTR2BDRD1DRD5 | |
| SCHEMBL11103715 | 0.84 | DRD1 (0.70) | HTR2AHTR2CHTR2BDRD1DRD5 | |
| SCHEMBL8769399 | 0.82 | HTR2A (0.63) | HTR2AHTR2CHTR2BDRD1DRD5 | |
| SCHEMBL10690380 | 0.82 | DRD1 (0.71) | DRD1DRD5DRD2MAPK1ADCY5 | |
| Bromide SCHEMBL10691988 | 0.81 | DRD1 (0.72) | DRD1DRD5DRD2MAPK1ADCY5 | |
| SCHEMBL10693049 | 0.81 | HTR2C (0.60) | HTR2AHTR2CHTR2BDRD1DRD5 | |
| SCHEMBL10691620 | 0.81 | HTR2C (0.60) | HTR2AHTR2CHTR2BDRD1DRD5 | |
| SCHEMBL10692914 | 0.80 | HTR2A (0.59) | HTR2AHTR2CHTR2BDRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4751222-A | 2,3,4,5-tetrahydro-1H-3-benzazepines and CNS affecting use thereof | NOVO INDUSTRI A/S (DK) | 1988-06-14 | — | — | US | disclosed |
| EP-0200455-A2 | 2,3,4,5-tetrahydro-1H-3-benzazepines substituted in position 5 | NOVO NORDISK A/S (DK) | 1986-11-05 | — | — | EP | disclosed |