Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7760476 | 0.89 | KMT2A (0.47) | KMT2AALDH1A1KDM4EMEN1NPC1 | |
| SCHEMBL9626241 | 0.86 | ALDH1A1 (0.38) | KMT2AALDH1A1KDM4EMEN1NPC1 | |
| SCHEMBL5265016 | 0.84 | KMT2A (0.56) | KMT2AALDH1A1KDM4EMEN1NPC1 | |
| SCHEMBL11084120 | 0.84 | ALDH1A1 (0.39) | KMT2AALDH1A1KDM4EMEN1NPC1 | |
| SCHEMBL9812280 | 0.82 | TDP1 (0.39) | KMT2AALDH1A1KDM4EMEN1NPC1 | |
| SCHEMBL11567828 | 0.80 | ALDH1A1 (0.42) | KMT2AALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL9640851 | 0.75 | ALDH1A1 (0.43) | KMT2AALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL4710387 | 0.74 | MAPT (0.54) | KMT2AALDH1A1KDM4EMEN1NPC1 | |
| SCHEMBL809274 | 0.74 | KMT2A (0.55) | KMT2AALDH1A1KDM4EMEN1POLB | |
| SCHEMBL10583759 | 0.73 | ALDH1A1 (0.42) | KMT2AALDH1A1KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255890-A1 | Process for the reaction of amines with heterocyclic reactive compounds | BAYER AG (DE) | 1988-02-17 | — | — | EP | disclosed |