Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.47 |
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | NQO2 | P16083 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5265016 | 0.94 | KMT2A (0.56) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL11084120 | 0.90 | ALDH1A1 (0.39) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL9812280 | 0.89 | TDP1 (0.39) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL10692489 | 0.89 | KMT2A (0.38) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL7760052 | 0.83 | RAB9A (0.57) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL9640851 | 0.81 | ALDH1A1 (0.43) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL4710387 | 0.80 | MAPT (0.54) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL809274 | 0.80 | KMT2A (0.55) | KMT2AMEN1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11567828 | 0.79 | ALDH1A1 (0.42) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL10583759 | 0.79 | ALDH1A1 (0.42) | KMT2ARAB9ANPC1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891182-B1 | ENZYME ASSISTED DYEING OF KERATINOUS FIBRES | NOVOZYMES AS (DK) | 2001-11-14 | — | — | EP | claimed |
| EP-0863950-B1 | HAIR DYEING COMPOSITION | NOVOZYMES AS (DK) | 2001-10-10 | — | — | EP | claimed |
| EP-0865465-B1 | LACCASES WITH IMPROVED DYEING PROPERTIES | NOVOZYMES AS (DK) | 2001-05-30 | — | — | EP | claimed |