SCHEMBL10692552

SCHEMBL10692552

CC(N(C)S(=O)(=O)c1cc(Cl)c(N)cc1Cl)S(=O)(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.51
CA12 O43570 4/20 0.38
CA1 P00915 4/20 0.38
CA2 P00918 4/20 0.38
CA9 Q16790 4/20 0.38
CA3 P07451 3/20 0.38
CA4 P22748 3/20 0.38
CA6 P23280 3/20 0.38
CA5A P35218 3/20 0.38
CA7 P43166 3/20 0.38
CA14 Q9ULX7 3/20 0.38
CA5B Q9Y2D0 3/20 0.38
TSHR P16473 3/20 0.37
CYP3A4 P08684 1/20 0.37
THRB P10828 1/20 0.37
HPGD P15428 1/20 0.37
ALOX15 P16050 1/20 0.37
CASP1 P29466 1/20 0.37
RECQL P46063 1/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11516387 0.79 ALDH1A1 (0.46) ALDH1A1CA12CA1CA2CA9
SCHEMBL1008822 0.79 ALDH1A1 (0.79) ALDH1A1CA12CA1CA2CA9
SCHEMBL10692557 0.74 ALDH1A1 (0.49) ALDH1A1CA12CA1CA2CA9
SCHEMBL11283353 0.73 ALDH1A1 (0.47) ALDH1A1CA12CA1CA2CA9
SCHEMBL10688911 0.73 CA12 (0.38) ALDH1A1CA12CA1CA2CA9
SCHEMBL1708535 0.73 GAA (0.52) ALDH1A1CA12CA1CA2CA9
SCHEMBL29516458 0.73 GAA (0.52) ALDH1A1CA12CA1CA2CA9
SCHEMBL11122867 0.72 CA12 (0.43) ALDH1A1CA12CA1CA2CA9
Dimethylformamide SCHEMBL27770247 0.72 ALDH1A1 (0.46) ALDH1A1CA12CA1CA2CA9
SCHEMBL11657083 0.71 ALDH1A1 (0.47) ALDH1A1CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4754024-A Fibre-reactive azo dyes containing vinylsulfonyl or analogous groups CIBA-GEIGY CORPORATION 1988-06-28 US disclosed
EP-0112285-B1 REACTIVE DYES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1987-03-18 EP disclosed
EP-0112285-A2 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1984-06-27 EP disclosed