SCHEMBL1008822

SCHEMBL1008822

CN(C)S(=O)(=O)c1cc(Cl)c(N)cc1Cl

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.79
TSHR P16473 2/20 0.47
GLA P06280 1/20 0.47
GAA P10253 1/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA3 P07451 1/20 0.46
CA4 P22748 1/20 0.46
CA6 P23280 1/20 0.46
CA5A P35218 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
CA5B Q9Y2D0 1/20 0.46
GSTO1 P78417 6/20 0.45
MAPT P10636 1/20 0.44
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
KCNJ6 P48051 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11438398 0.89 ALDH1A1 (1.00) ALDH1A1TSHRGLACA12CA1
SCHEMBL11689195 0.86 ALDH1A1 (0.82) ALDH1A1TSHRGLAGAACA12
SCHEMBL11689176 0.84 ALDH1A1 (0.72) ALDH1A1TSHRGLACA12CA1
SCHEMBL11064253 0.84 ALDH1A1 (0.72) ALDH1A1TSHRGLACA12CA1
SCHEMBL11686575 0.84 ALDH1A1 (0.57) ALDH1A1TSHRGLAGAACA12
SCHEMBL7214233 0.84 ALDH1A1 (0.66) ALDH1A1TSHRGLAGSTO1MAPT
SCHEMBL8298291 0.82 ALDH1A1 (0.64) ALDH1A1TSHRMAPTMEN1KMT2A
SCHEMBL10691315 0.80 ALDH1A1 (0.53) ALDH1A1TSHRGAACA12CA1
SCHEMBL10692552 0.79 ALDH1A1 (0.51) ALDH1A1TSHRGLAGAACA12
SCHEMBL11684852 0.78 ALDH1A1 (0.69) ALDH1A1TSHRGLACA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6548647-B2 Spraying coupling components in solution or suspension to collide in reactor chamber, then pressurizing to remove; useful for offset printing inks CLARIANT GMBH (DE) 2003-04-15 US claimed
US-20020055619-A1 Process for preparing azo colorants CLARIANT GMBH 2002-05-09 US claimed
EP-1195411-A1 Process for the preparation of azo colourants Clariant GmbH (DE) 2002-04-10 EP claimed
US-8329369-B2 Method for the production of pure C.I. pigment orange 74 CLARIANT FINANCE (BVI) LIMITED (VG) 2012-12-11 US disclosed
EP-2170999-B1 METHOD FOR THE PRODUCTION OF PURE C.I. PIGMENT ORANGE 74 CLARIANT FINANCE BVI LTD (VG) 2011-01-05 EP disclosed
US-20100178607-A1 Method for the Production of Pure C.I. Pigment Orange 74 CLARIANT FINANCE (BVI) LIMITED (VG) 2010-07-15 US disclosed
EP-2170999-A2 METHOD FOR THE PRODUCTION OF PURE C.I. PIGMENT ORANGE 74 Clariant Finance (BVI) Limited (VG) 2010-04-07 EP disclosed
WO-2009000375-A2 METHOD FOR THE PRODUCTION OF PURE C.I. PIGMENT ORANGE 74 CLARIANT FINANCE (BVI) LIMITED (VG) 2008-12-31 WO disclosed
EP-1417264-B1 NOVEL AZO PIGMENTS CLARIANT PRODUKTE DEUTSCHLAND (DE) 2008-10-15 EP disclosed
US-7318863-B2 Azo pigment preparations for packaging gravure and flexographic printing CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2008-01-15 US disclosed
US-7309389-B2 Preparation of azo colorants in microreactors and their use in electrophotographic toners and developers, powder coatings, ink jet inks and electronic medias CLARIANT FINANCE (BVI) LIMITED (VG) 2007-12-18 US disclosed
US-4879373-A AZO DYES SANDOZ LTD. (CH) 1989-11-07 US disclosed
US-4754024-A Fibre-reactive azo dyes containing vinylsulfonyl or analogous groups CIBA-GEIGY CORPORATION 1988-06-28 US disclosed
EP-0112285-B1 REACTIVE DYES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1987-03-18 EP disclosed
US-4623397-A GOOD FASTNESS SANDOZ LTD. (CH) 1986-11-18 US disclosed
EP-0112285-A2 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1984-06-27 EP disclosed
US-4257942-A New water-insoluble azo dyes AZIENDE COLORI NAZIONALI AFFINI ACNA S.P.A. (IT) 1981-03-24 US disclosed
US-4136033-A DIAZO COUPLERS SANDOZ LTD. (CH) 1979-01-23 US disclosed
US-4046756-A HYDROPHOBIC TEXTILES SANDOZ LTD. (CH) 1977-09-06 US disclosed
US-4026931-A AZO DYES, FIBER-REACTIVE; INDOLE OR 5-AMINO-PYRAZOLE COUPLING COMPONENT BAYER AKTIENGESELLSCHAFT (DT) 1977-05-31 US disclosed