Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693391 | 0.88 | MAPK1 (0.41) | HPGDL3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL10692962 | 0.72 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2GLAHPGDATM | |
| SCHEMBL135162 | 0.65 | ATM (1.00) | ALDH1A1SMN1; SMN2HPGDATMTDP1 | |
| SCHEMBL9324919 | 0.65 | ATM (1.00) | ALDH1A1SMN1; SMN2HPGDATMTDP1 | |
| SCHEMBL1499201 | 0.64 | ALDH1A1 (0.54) | ALDH1A1HPGDATMTDP1L3MBTL1 | |
| SCHEMBL134024 | 0.63 | ATM (0.95) | ALDH1A1SMN1; SMN2HPGDATMTDP1 | |
| SCHEMBL134300 | 0.63 | ATM (0.95) | ALDH1A1SMN1; SMN2HPGDATMTDP1 | |
| SCHEMBL314267 | 0.63 | ALDH1A1 (0.93) | ALDH1A1HPGDATMTDP1L3MBTL1 | |
| SCHEMBL9066312 | 0.63 | ALDH1A1 (0.93) | ALDH1A1HPGDATMTDP1L3MBTL1 | |
| Benzophenone SCHEMBL27708529 | 0.62 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2GLAHPGDATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778792-A | Use of 7-acyl benzoxazinones and their derivatives in treating atheromatous disorders | LABORATORIES NEGMA (FR) | 1988-10-18 | — | — | US | disclosed |