Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691134 | 0.88 | MAPK1 (0.41) | ALDH1A1SMN1; SMN2HPGDMAPTTDP1 | |
| SCHEMBL7356037 | 0.74 | MAOA (0.43) | ALDH1A1RAB9AHPGDMAPTTDP1 | |
| SCHEMBL10693858 | 0.73 | RAB9A (0.46) | ALDH1A1NPC1RAB9ASMN1; SMN2GLA | |
| SCHEMBL10692566 | 0.72 | ALDH1A1 (0.45) | ALDH1A1NPC1RAB9ASMN1; SMN2GLA | |
| SCHEMBL10738804 | 0.71 | ALDH1A1 (0.44) | ALDH1A1NPC1SMN1; SMN2GLAHPGD | |
| SCHEMBL9666427 | 0.70 | ALDH1A1 (0.45) | ALDH1A1NPC1RAB9ASMN1; SMN2GLA | |
| SCHEMBL14565102 | 0.70 | CYP11B2 (0.49) | ALDH1A1NPC1RAB9ASMN1; SMN2GLA | |
| SCHEMBL10736621 | 0.70 | SMN1; SMN2 (0.43) | ALDH1A1RAB9ASMN1; SMN2GLAHPGD | |
| SCHEMBL4304620 | 0.69 | NOTUM (0.61) | ALDH1A1NPC1RAB9ASMN1; SMN2GLA | |
| SCHEMBL10848994 | 0.68 | PDE5A (0.42) | ALDH1A1NPC1RAB9ASMN1; SMN2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778792-A | Use of 7-acyl benzoxazinones and their derivatives in treating atheromatous disorders | LABORATORIES NEGMA (FR) | 1988-10-18 | — | — | US | disclosed |