Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5680244 | 0.88 | HTT (0.55) | HTTPARP1AKR1C1MEN1KMT2A | |
| SCHEMBL8425730 | 0.81 | HTT (0.56) | HTTPARP1AKR1C1MEN1KMT2A | |
| SCHEMBL8415759 | 0.79 | HTT (0.59) | HTTPARP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8424385 | 0.77 | HTT (0.46) | HTTTACR1PARP1AKR1C1MEN1 | |
| Zinc Ion SCHEMBL9784446 | 0.76 | PARP1 (0.51) | HTTPARP1AKR1C1MEN1KMT2A | |
| SCHEMBL6044375 | 0.76 | MRGPRX4 (0.51) | HTTKMT2AMRGPRX4 | |
| SCHEMBL4415350 | 0.75 | HTT (0.75) | HTTPARP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5680240 | 0.74 | APEX1 (0.58) | HTTPARP1AKR1C1MEN1KMT2A | |
| SCHEMBL18719963 | 0.74 | EGFR (0.47) | HTTMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL9574717 | 0.74 | HTT (0.73) | HTTPARP1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262810-A2 | Sheet recording material containing dye-forming components | Fuji Photo Film Co., Ltd. (JP) | 1988-04-06 | — | — | EP | disclosed |