Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | PARP1 | P09874 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | RXRG | P48443 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9574717 | 0.89 | HTT (0.73) | HTTKMT2ASMN1; SMN2ALDH1A1PARP1 | |
| SCHEMBL4415350 | 0.87 | HTT (0.75) | HTTKMT2ASMN1; SMN2ALDH1A1PARP1 | |
| SCHEMBL5680244 | 0.87 | HTT (0.55) | HTTKMT2ASMN1; SMN2ALDH1A1PARP1 | |
| SCHEMBL5839101 | 0.84 | ALDH1A1 (0.59) | HTTKMT2ASMN1; SMN2ALDH1A1PARP1 | |
| SCHEMBL8425730 | 0.84 | HTT (0.56) | HTTKMT2ASMN1; SMN2ALDH1A1PARP1 | |
| SCHEMBL340937 | 0.83 | HTT (0.69) | HTTKMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL5296788 | 0.83 | KMT2A (0.58) | HTTKMT2ASMN1; SMN2ALDH1A1PARP1 | |
| SCHEMBL31538458 | 0.83 | ALDH1A1 (0.56) | HTTKMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL1646770 | 0.82 | LRRK2 (0.56) | HTTKMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL21791006 | 0.81 | ALDH1A1 (0.78) | HTTKMT2AALDH1A1KDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880064-A | COMPRISING A SOLVENT FREE OF AN UMPLEASANT ODOR AND FRIENDLY TO THE ENVIRONMENT | MITSUBISHI PAPER MILLS LTD. (JP) | 1999-03-09 | — | — | US | disclosed |