Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | PARP1 | P09874 | 2/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8425730 | 0.89 | HTT (0.56) | HTTPARP1AKR1C1MEN1KMT2A | |
| SCHEMBL10692624 | 0.88 | HTT (0.47) | HTTPARP1AKR1C1MEN1KMT2A | |
| Zinc Ion SCHEMBL9784446 | 0.87 | PARP1 (0.51) | HTTPARP1AKR1C1MEN1KMT2A | |
| SCHEMBL8415759 | 0.87 | HTT (0.59) | HTTPARP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5680240 | 0.85 | APEX1 (0.58) | HTTPARP1AKR1C1MEN1KMT2A | |
| SCHEMBL8424385 | 0.84 | HTT (0.46) | HTTPARP1AKR1C1MEN1KMT2A | |
| SCHEMBL9784448 | 0.84 | APEX1 (0.57) | HTTPARP1AKR1C1MEN1KMT2A | |
| SCHEMBL4415350 | 0.83 | HTT (0.75) | HTTPARP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9574717 | 0.81 | HTT (0.73) | HTTPARP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL340937 | 0.79 | HTT (0.69) | HTTMEN1KMT2ASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1291196-B1 | Heat-sensitive recording material | FUJI PHOTO FILM CO LTD (JP) | 2006-06-21 | — | — | EP | disclosed |
| EP-1622858-A2 | HEAT SENSITIVE RECORDING MATERIAL | Ciba SC Holding AG (CH) | 2006-02-08 | — | — | EP | disclosed |
| US-6890880-B2 | Heat-sensitive recording material | FUJI PHOTO FILM CO., LTD. (JP) | 2005-05-10 | — | — | US | disclosed |
| WO-2004099116-A2 | HEAT SENSITIVE RECORDING MATERIAL | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-11-18 | — | — | WO | disclosed |
| US-20030087758-A1 | Heat-sensitive recording material | FUJI PHOTO FIL CO., LTD. | 2003-05-08 | — | — | US | disclosed |
| EP-1291196-A2 | Heat-sensitive recording material | FUJI PHOTO FILM CO., LTD. (JP) | 2003-03-12 | — | — | EP | disclosed |