Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10687380 | 0.90 | ALDH1A1 (0.47) | USP2ALDH1A1TSHRLMNAMAPT | |
| SCHEMBL8770626 | 0.88 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNAMAPTSMN1; SMN2 | |
| SCHEMBL8770555 | 0.88 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNAMAPTSMN1; SMN2 | |
| SCHEMBL8770604 | 0.88 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNAMAPTSMN1; SMN2 | |
| SCHEMBL8770571 | 0.88 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNAMAPTSMN1; SMN2 | |
| SCHEMBL10691305 | 0.88 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNAMAPTSMN1; SMN2 | |
| SCHEMBL7230903 | 0.88 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNAMAPTSMN1; SMN2 | |
| SCHEMBL10635243 | 0.88 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNAMAPTSMN1; SMN2 | |
| SCHEMBL8770752 | 0.88 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNAMAPTSMN1; SMN2 | |
| SCHEMBL8770498 | 0.88 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4734522-A | LIQUID CRYSTALS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-03-29 | — | — | US | disclosed |
| US-4578210-A | Carbocyclic six-membered ring compounds | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1986-03-25 | — | — | US | disclosed |
| EP-0134576-A2 | Carbocyclic six-membered ring compounds | MERCK PATENT GmbH (DE) | 1985-03-20 | — | — | EP | disclosed |
| US-4163006-A | AGAINST OXIDATIVE AND UV LIGHT DEGRADATION | CIBA-GEIGY CORPORATION (US) | 1979-07-31 | — | — | US | disclosed |