Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | FPR2 | P25090 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.59 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.59 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.59 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.59 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690937 | 0.86 | CASR (0.62) | SMN1; SMN2KDM4ENPC1RAB9AKMT2A | |
| SCHEMBL8974580 | 0.85 | POLB (0.65) | PLAAT5PLAAT4KMT2ACNR1 | |
| SCHEMBL28414032 | 0.85 | POLB (0.65) | PLAAT5PLAAT4KMT2ACNR1 | |
| SCHEMBL10839731 | 0.85 | KMT2A (0.52) | GAASMN1; SMN2KDM4ETDP1FPR2 | |
| SCHEMBL8098635 | 0.83 | ALDH1A1 (0.62) | GAASMN1; SMN2PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL9542025 | 0.83 | GLI1 (0.58) | GAAKDM4EPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL13883466 | 0.83 | GLI1 (0.58) | GAAKDM4EPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL10977174 | 0.82 | KMT2A (0.55) | GAASMN1; SMN2KDM4ETDP1FPR2 | |
| SCHEMBL10693452 | 0.82 | SMN1; SMN2 (0.57) | GAASMN1; SMN2KDM4ETDP1FPR2 | |
| SCHEMBL17204643 | 0.82 | NAAA (0.54) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | disclosed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |
| US-4052506-A | BENZAZEPINES | SMITHKLINE CORPORATION (US) | 1977-10-04 | — | — | US | disclosed |
| US-4011319-A | STIMULATING DOPAMINE RECEPTORS, RENAL VASODILATORS, DIURETICS | SMITHKLINE CORPORATION (US) | 1977-03-08 | — | — | US | disclosed |