Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22734800 | 0.77 | CYP2C19 (0.41) | MAPK1TSHRCYP2C19HIF1AALDH1A1 | |
| SCHEMBL2532155 | 0.76 | MAPK1 (0.46) | MAPK1TSHRCYP2C19HIF1AALDH1A1 | |
| SCHEMBL9079829 | 0.76 | ALDH1A1 (0.39) | TSHRALDH1A1 | |
| SCHEMBL22730218 | 0.76 | MAPK1 (0.46) | MAPK1TSHRCYP2C19HIF1AALDH1A1 | |
| SCHEMBL9078592 | 0.75 | MAPK1 (0.41) | MAPK1TSHRCYP2C19HIF1AALDH1A1 | |
| SCHEMBL22730164 | 0.75 | CYP2C19 (0.39) | MAPK1TSHRCYP2C19HIF1AALDH1A1 | |
| SCHEMBL22730160 | 0.73 | MAPK1 (0.35) | MAPK1TSHRCYP2C19HIF1AALDH1A1 | |
| SCHEMBL8201774 | 0.72 | TSHR (0.48) | MAPK1TSHRCYP2C19ALDH1A1TAAR1 | |
| SCHEMBL22730158 | 0.72 | CYP2C19 (0.37) | MAPK1TSHRCYP2C19HIF1AALDH1A1 | |
| SCHEMBL22730227 | 0.72 | MAPK1 (0.42) | MAPK1TSHRCYP2C19HIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263673-A2 | Addition reaction of hydrosilanes with unsaturated hydrocarbons | Toray Silicone Company, Ltd. (JP) | 1988-04-13 | — | — | EP | disclosed |