Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | KCNN4 | O15554 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692727 | 0.72 | MAPK1 (0.44) | TSHRKCNN4ALDH1A1CYP1A2MAPK1 | |
| SCHEMBL835731 | 0.71 | KCNN4 (0.42) | TSHRKCNN4ALDH1A1MAPK1TAAR1 | |
| SCHEMBL9078592 | 0.69 | MAPK1 (0.41) | TSHRKCNN4ALDH1A1CYP1A2MAPK1 | |
| SCHEMBL8322042 | 0.65 | MAPK1 (0.42) | TSHRKCNN4ALDH1A1CYP1A2MAPK1 | |
| SCHEMBL6324960 | 0.65 | TSHR (0.42) | TSHRKCNN4ALDH1A1CYP1A2TAAR1 | |
| SCHEMBL819164 | 0.65 | TSHR (0.65) | TSHRKCNN4ALDH1A1CYP1A2MAPK1 | |
| SCHEMBL151981 | 0.65 | TSHR (0.65) | TSHRKCNN4ALDH1A1CYP1A2MAPK1 | |
| SCHEMBL10940043 | 0.65 | TSHR (0.65) | TSHRKCNN4ALDH1A1CYP1A2MAPK1 | |
| Chlorotriphenylmethane SCHEMBL461 | 0.65 | TSHR (0.65) | TSHRKCNN4ALDH1A1CYP1A2MAPK1 | |
| Chlorotriphenylmethane SCHEMBL16781670 | 0.65 | TSHR (0.65) | TSHRKCNN4ALDH1A1CYP1A2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022987-A | Aryl substituted alkylsilanes and a preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2000-02-08 | — | — | US | claimed |