Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAOA | P21397 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylformamide SCHEMBL28133389 | 0.82 | MAPT (0.67) | TSHRALDH1A1MAPTCYP3A4TDP1 | |
| Aniline SCHEMBL78839 | 0.81 | TSHR (0.65) | TSHRRECQLALDH1A1MAOAMAPT | |
| Aniline SCHEMBL7501280 | 0.81 | TSHR (0.73) | TSHRRECQLALDH1A1MAOAMAPT | |
| Aniline SCHEMBL27632885 | 0.80 | TSHR (0.55) | TSHRALDH1A1MAOAMAPTCYP3A4 | |
| Benzidine SCHEMBL28749026 | 0.80 | CYP3A4 (0.55) | TSHRRECQLALDH1A1MAPTCYP3A4 | |
| Biphenyl SCHEMBL27802171 | 0.79 | ALDH1A1 (0.50) | TSHRRECQLALDH1A1MAPTKDM4E | |
| Aniline SCHEMBL7406312 | 0.78 | TSHR (0.69) | TSHRRECQLALDH1A1MAOAMAPT | |
| Aniline SCHEMBL27447053 | 0.78 | TSHR (0.69) | TSHRRECQLALDH1A1MAOAMAPT | |
| Aniline SCHEMBL5053979 | 0.78 | TSHR (0.69) | TSHRRECQLALDH1A1MAOAMAPT | |
| Aniline SCHEMBL11121974 | 0.78 | TSHR (0.69) | TSHRRECQLALDH1A1MAOAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4754024-A | Fibre-reactive azo dyes containing vinylsulfonyl or analogous groups | CIBA-GEIGY CORPORATION | 1988-06-28 | — | — | US | disclosed |
| EP-0112285-B1 | REACTIVE DYES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1987-03-18 | — | — | EP | disclosed |