Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 3/20 | 0.65 |
| ▸ | S100A4 | P26447 | 2/20 | 0.65 |
| ▸ | BCHE | P06276 | 1/20 | 0.62 |
| ▸ | ACHE | P22303 | 1/20 | 0.62 |
| ▸ | CES1 | P23141 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | CASP6 | P55212 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28115063 | 0.91 | PTPRC (0.54) | PTPRCS100A4BCHEACHECES1 | |
| SCHEMBL7930693 | 0.84 | CASP6 (0.48) | PTPRCS100A4BCHEACHECES1 | |
| SCHEMBL11207794 | 0.83 | PTPRC (0.83) | PTPRCS100A4BCHEACHECES1 | |
| SCHEMBL2772220 | 0.83 | PTPRC (0.83) | PTPRCS100A4BCHEACHECES1 | |
| SCHEMBL11245984 | 0.81 | PTPRC (0.67) | PTPRCS100A4BCHEACHECES1 | |
| SCHEMBL7928287 | 0.80 | P2RY2 (0.48) | PTPRCS100A4BCHEACHECES1 | |
| SCHEMBL8104719 | 0.80 | PTPRC (0.84) | PTPRCS100A4BCHEACHECES1 | |
| SCHEMBL30375977 | 0.80 | PTPRC (0.84) | PTPRCS100A4BCHEACHECES1 | |
| SCHEMBL10939924 | 0.79 | PTPRC (0.65) | PTPRCS100A4BCHEACHECES1 | |
| SCHEMBL10603975 | 0.79 | ALDH1A1 (0.67) | PTPRCS100A4BCHEACHECES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4739062-A | REACTING AN AROMATIC COMPOUND WITH DICARBOXYLIC ACID COMPOUND USING METAL HALIDE CATALYST | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1988-04-19 | — | — | US | disclosed |