Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | CASP6 | P55212 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694756 | 0.92 | RAPGEF4 (0.40) | RAPGEF4KDM4EALDH1A1POLBGAA | |
| SCHEMBL10694725 | 0.92 | RAPGEF4 (0.40) | RAPGEF4KDM4EALDH1A1POLBGAA | |
| SCHEMBL10696544 | 0.87 | RAPGEF4 (0.36) | RAPGEF4KDM4EALDH1A1POLBGAA | |
| SCHEMBL9878790 | 0.87 | CA2 (0.41) | RAPGEF4KDM4EALDH1A1POLBGAA | |
| SCHEMBL17774703 | 0.85 | RAPGEF4 (0.39) | RAPGEF4KDM4EALDH1A1POLBGAA | |
| SCHEMBL10625532 | 0.84 | RAPGEF4 (0.38) | RAPGEF4KDM4EALDH1A1POLBGAA | |
| SCHEMBL8164203 | 0.84 | RAPGEF4 (0.58) | RAPGEF4KDM4EALDH1A1POLBGAA | |
| SCHEMBL9809133 | 0.84 | APEX1 (0.42) | RAPGEF4KDM4EALDH1A1POLBGAA | |
| SCHEMBL10389511 | 0.83 | CYP2D6 (0.42) | RAPGEF4KDM4EALDH1A1POLBGAA | |
| SCHEMBL10388848 | 0.82 | RAPGEF4 (0.36) | RAPGEF4KDM4EALDH1A1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4785099-A | FIBER-REACTIVE DYES FOR CELLULOSE | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-15 | — | — | US | disclosed |
| EP-0229339-A2 | Water soluble triphene dioxazine compounds, their starting compounds containing sulphonyl groups, process for their preparation and use of the triphene dioxazines as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-07-22 | — | — | EP | disclosed |