Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | POLA1 | P09884 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1261691 | 1.00 | PPM1B (0.35) | PPM1BPTPN1PPP1CCHTTATM | |
| SCHEMBL10329694 | 1.00 | PPM1B (0.35) | PPM1BPTPN1PPP1CCHTTATM | |
| Hydrochloric Acid SCHEMBL11134893 | 0.98 | PPM1B (0.34) | PPM1BPTPN1PPP1CCHTTATM | |
| SCHEMBL2690895 | 0.90 | HTT (0.35) | HTTATMALDH1A1HSD17B10LMNA | |
| SCHEMBL2690901 | 0.90 | HTT (0.35) | HTTATMALDH1A1HSD17B10LMNA | |
| SCHEMBL2690897 | 0.90 | HTT (0.35) | HTTATMALDH1A1HSD17B10LMNA | |
| SCHEMBL6662594 | 0.83 | APLNR (0.32) | CYP1A2APLNRCYP2D6 | |
| SCHEMBL5246594 | 0.82 | APLNR (0.41) | ALDH1A1HSD17B10CYP1A2APLNRKMT2A | |
| SCHEMBL3385056 | 0.82 | APLNR (0.41) | ALDH1A1HSD17B10CYP1A2APLNRKMT2A | |
| SCHEMBL11260869 | 0.82 | APLNR (0.41) | ALDH1A1HSD17B10CYP1A2APLNRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4739071-A | Process for the preparation of enantiomers | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-04-19 | — | — | US | disclosed |