Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5246594 | 1.00 | APLNR (0.41) | APLNRCYP1A2KDM4ECYP2D6MAPT | |
| SCHEMBL3385056 | 1.00 | APLNR (0.41) | APLNRCYP1A2KDM4ECYP2D6MAPT | |
| SCHEMBL9862088 | 0.88 | APLNR (0.35) | APLNRCYP1A2KDM4ECYP2D6MAPT | |
| SCHEMBL359379 | 0.88 | APLNR (0.35) | APLNRCYP1A2KDM4ECYP2D6MAPT | |
| SCHEMBL9862146 | 0.88 | APLNR (0.35) | APLNRCYP1A2KDM4ECYP2D6MAPT | |
| SCHEMBL9862392 | 0.88 | APLNR (0.35) | APLNRCYP1A2KDM4ECYP2D6MAPT | |
| SCHEMBL9909013 | 0.88 | APLNR (0.35) | APLNRCYP1A2KDM4ECYP2D6MAPT | |
| SCHEMBL9909003 | 0.88 | APLNR (0.35) | APLNRCYP1A2KDM4ECYP2D6MAPT | |
| Hydrochloric Acid SCHEMBL11138045 | 0.86 | APLNR (0.33) | APLNRCYP1A2KDM4ECYP2D6MAPT | |
| Hydrochloric Acid SCHEMBL11136901 | 0.86 | APLNR (0.33) | APLNRCYP1A2KDM4ECYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332745-A | Preparation of 2-cyano-3,3-dimethyl-cyclopropane-1-carboxylic acid esters and intermediates therefor | BAYER AKTIENGESELLSCHAFT (DE) | 1982-06-01 | — | — | US | disclosed |
| US-4307033-A | Preparation of 3,3-dimethyl-cyclopropane-1,1,2-tricarboxylic acid derivatives and intermediates therefor | BAYER AKTIENGESELLSCHAFT (DE) | 1981-12-22 | — | — | US | disclosed |
| EP-0021160-A1 | Process for the preparation of trans-3,3-dimethyl-cyclopropane-1,2-dicarboxylic acid | BAYER AG (DE) | 1981-01-07 | — | — | EP | disclosed |
| EP-0021160-A1 | Process for the preparation of trans-3,3-dimethyl-cyclopropane-1,2-dicarboxylic acid | BAYER AG (DE) | 1981-01-07 | — | — | EP | disclosed |