SCHEMBL10692880

SCHEMBL10692880

C=Cc1ccccc1C=C.c1ccc2c(c1)CC2.c1ccc2c(c1)CC2

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
TSHR P16473 3/20 0.46
CYP2A6 P11509 1/20 0.41
HTR2C P28335 3/20 0.40
CES1 P23141 1/20 0.37
MAOB P27338 3/20 0.36
ORAI1 Q96D31 1/20 0.36
ORAI2 Q96SN7 1/20 0.36
ORAI3 Q9BRQ5 1/20 0.36
PNMT P11086 1/20 0.36
CD44 P16070 1/20 0.36
DRD2 P14416 4/20 0.35
DRD1 P21728 3/20 0.34
DRD3 P35462 3/20 0.34
MAOA P21397 2/20 0.34
DRD4 P21917 2/20 0.34
DRD5 P21918 2/20 0.34
MIF P14174 1/20 0.34
ADRA1D P25100 3/20 0.33
ADRA1A P35348 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL473080 0.83 ALDH1A1 (0.63) ALDH1A1TSHRCYP2A6LMNAHSD17B10
SCHEMBL7638 0.83 ALDH1A1 (0.63) ALDH1A1TSHRCYP2A6LMNAHSD17B10
SCHEMBL29405187 0.83 ALDH1A1 (0.63) ALDH1A1TSHRCYP2A6LMNAHSD17B10
SCHEMBL11016199 0.80 ALDH1A1 (0.60) ALDH1A1TSHRCYP2A6LMNAHSD17B10
SCHEMBL8719955 0.80 ALDH1A1 (0.60) ALDH1A1TSHRCYP2A6LMNAHSD17B10
SCHEMBL1176773 0.80 ALDH1A1 (0.60) ALDH1A1TSHRCYP2A6LMNAHSD17B10
Charcoal, Activated SCHEMBL6411785 0.80 ALDH1A1 (0.60) ALDH1A1TSHRCYP2A6LMNAHSD17B10
Ethylene SCHEMBL7946796 0.80 ALDH1A1 (0.60) ALDH1A1TSHRCYP2A6LMNATP53
SCHEMBL22496001 0.80 ALDH1A1 (0.60) ALDH1A1TSHRCYP2A6LMNAHSD17B10
SCHEMBL9562250 0.80 ALDH1A1 (0.60) ALDH1A1TSHRLMNAHSD17B10TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4783514-A Polymeric monoarylcyclobutane compositions THE DOW CHEMICAL COMPANY (US) 1988-11-08 US disclosed