SCHEMBL10692923

SCHEMBL10692923

O=C1OC(=O)N1Nc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.57
TDP1 Q9NUW8 4/20 0.48
ALDH1A1 P00352 8/20 0.47
MAPT P10636 8/20 0.47
NPSR1 Q6W5P4 4/20 0.47
ALOX12 P18054 3/20 0.47
GAA P10253 3/20 0.47
HPGD P15428 2/20 0.47
CACNA1B Q00975 2/20 0.47
APBA1 Q02410 2/20 0.47
CCR6 P51684 2/20 0.47
CASP6 P55212 1/20 0.44
LMNA P02545 3/20 0.41
HSP90AA1 P07900 2/20 0.41
HCRTR1 O43613 1/20 0.41
S1PR4 O95977 1/20 0.41
S1PR1 P21453 1/20 0.41
HTT P42858 1/20 0.38
HSD17B10 Q99714 2/20 0.36
CTSD P07339 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18677769 0.74 CYP1A2 (0.59) CYP1A2TDP1ALDH1A1MAPTNPSR1
SCHEMBL87617 0.74 CYP1A2 (0.59) CYP1A2TDP1ALDH1A1MAPTNPSR1
SCHEMBL8735062 0.74 CYP1A2 (0.48) CYP1A2TDP1ALDH1A1MAPTNPSR1
SCHEMBL3259551 0.73 CYP1A2 (1.00) CYP1A2TDP1ALDH1A1MAPTNPSR1
SCHEMBL4394297 0.73 CYP1A2 (0.57) CYP1A2TDP1ALDH1A1MAPTNPSR1
SCHEMBL8141682 0.71 CYP1A2 (0.67) CYP1A2TDP1ALDH1A1MAPTNPSR1
Hydrochloric Acid SCHEMBL5138493 0.71 CYP1A2 (0.96) CYP1A2TDP1ALDH1A1MAPTNPSR1
SCHEMBL11945529 0.71 CYP1A2 (0.67) CYP1A2TDP1ALDH1A1MAPTNPSR1
SCHEMBL11213475 0.70 CYP1A2 (0.53) CYP1A2TDP1ALDH1A1MAPTNPSR1
SCHEMBL28110623 0.68 HSP90AA1 (0.61) CYP1A2TDP1ALDH1A1MAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4772747-A Preparation of 2,4,6-trichlorophenylhydrazine EASTMAN KODAK COMPANY (US) 1988-09-20 US disclosed