Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CASP6 | P55212 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.47 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.47 |
| ▸ | CCR6 | P51684 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | PARL | Q9H300 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11213475 | 0.91 | CYP1A2 (0.53) | CYP1A2TDP1CASP6ALDH1A1MAPT | |
| SCHEMBL8291675 | 0.82 | MAPK13 (0.53) | CYP1A2TDP1ALDH1A1MAPTNPSR1 | |
| SCHEMBL9769577 | 0.75 | CYP1A2 (0.50) | CYP1A2TDP1CASP6ALDH1A1MAPT | |
| SCHEMBL87617 | 0.74 | CYP1A2 (0.59) | CYP1A2TDP1CASP6ALDH1A1MAPT | |
| SCHEMBL18677769 | 0.74 | CYP1A2 (0.59) | CYP1A2TDP1CASP6ALDH1A1MAPT | |
| SCHEMBL8735062 | 0.74 | CYP1A2 (0.48) | CYP1A2TDP1CASP6ALDH1A1MAPT | |
| SCHEMBL31279742 | 0.73 | MEN1 (0.52) | TDP1ALDH1A1MAPTNPSR1GAA | |
| SCHEMBL9769551 | 0.73 | TDP1 (0.45) | CYP1A2TDP1CASP6ALDH1A1MAPT | |
| SCHEMBL10692923 | 0.73 | CYP1A2 (0.57) | CYP1A2TDP1CASP6ALDH1A1MAPT | |
| SCHEMBL3259551 | 0.73 | CYP1A2 (1.00) | CYP1A2TDP1CASP6ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12202806-B2 | Eco-friendly materials and methods for renewable and sustainable applications in material chemistry | NDSU RESEARCH FOUNDATION (US) | 2025-01-21 | — | — | US | disclosed |
| US-20210163424-A1 | ECO-FRIENDLY MATERIALS AND METHODS FOR RENEWABLE AND SUSTAINABLE APPLICATIONS IN MATERIAL CHEMISTRY | NATIONAL SCIENCE FOUNDATION | 2021-06-03 | — | — | US | disclosed |
| US-10919866-B2 | Eco-friendly materials and methods for renewable and sustainable applications in material chemistry | NDSU RESEARCH FOUNDATION (US) | 2021-02-16 | — | — | US | disclosed |
| US-20190047965-A1 | ECO-FRIENDLY MATERIALS AND METHODS FOR RENEWABLE AND SUSTAINABLE APPLICATIONS IN MATERIAL CHEMISTRY | NORTH DAKOTA STATE UNIVERSITY | 2019-02-14 | — | — | US | disclosed |
| WO-2017156066-A1 | ECO-FRIENDLY MATERIALS AND METHODS FOR RENEWABLE AND SUSTAINABLE APPLICATIONS IN MATERIAL CHEMISTRY | NDSU RESEARCH FOUNDATION (US) | 2017-09-14 | — | — | WO | disclosed |
| US-7517880-B2 | Inhibition of p38 kinase using symmetrical and unsymmetrical diphenyl ureas | BAYER PHARMACEUTICALS CORPORATION (US) | 2009-04-14 | — | — | US | disclosed |
| US-20090093526-A1 | INHIBITION OF P38 KINASE USING SYMMETRICAL AND UNSYMMETRICAL DIPHENYL UREAS | BAYER HEALTHCARE LLC | 2009-04-09 | — | — | US | disclosed |
| US-20080269265-A1 | Inhibition Of Raf Kinase Using Symmetrical And Unsymmetrical Substituted Diphenyl Ureas | MILLER SCOTT | 2008-10-30 | — | — | US | disclosed |
| EP-1616865-A1 | Inhibition of p38 kinase using symmetrical and unsymmetrical diphenyl ureas | Bayer Pharmaceuticals Corporation (US) | 2006-01-18 | — | — | EP | disclosed |
| EP-1042305-B1 | INHIBITION OF p38 KINASE USING SYMMETRICAL AND UNSYMMETRICAL DIPHENYL UREAS | BAYER PHARMACEUTICALS CORP (US) | 2005-06-08 | — | — | EP | disclosed |
| US-20040102636-A1 | Inhibition of p38 kinase using symmetrical and unsymmetrical diphenyl ureas | BAYER CORPORATION | 2004-05-27 | — | — | US | disclosed |
| EP-1042305-A4 | INHIBITION OF p38 KINASE USING SYMMETRICAL AND UNSYMMETRICAL DIPHENYL UREAS | BAYER AG (US) | 2003-05-14 | — | — | EP | disclosed |
| EP-1049664-A1 | INHIBITION OF RAF KINASE USING SYMMETRICAL AND UNSYMMETRICAL SUBSTITUTED DIPHENYL UREAS | Bayer Corporation (US) | 2000-11-08 | — | — | EP | disclosed |
| EP-1042305-A1 | INHIBITION OF p38 KINASE USING SYMMETRICAL AND UNSYMMETRICAL DIPHENYL UREAS | Bayer Corporation (US) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999032436-A1 | INHIBITION OF RAF KINASE USING SYMMETRICAL AND UNSYMMETRICAL SUBSTITUTED DIPHENYL UREAS | BAYER CORPORATION (US) | 1999-07-01 | — | — | WO | disclosed |
| WO-1999032463-A1 | INHIBITION OF p38 KINASE USING SYMMETRICAL AND UNSYMMETRICAL DIPHENYL UREAS | BAYER CORPORATION (US) | 1999-07-01 | — | — | WO | disclosed |
| EP-0257433-B1 | Method for the preparation of quinoline-2,3-dicarboxylic acid | AMERICAN CYANAMID CO (US) | 1994-03-23 | — | — | EP | disclosed |
| US-4772747-A | Preparation of 2,4,6-trichlorophenylhydrazine | EASTMAN KODAK COMPANY (US) | 1988-09-20 | — | — | US | disclosed |
| US-4757146-A | Method for the preparation of quinoline-2,3-dicarboxylic acid | AMERICAN CYANAMID COMPANY (US) | 1988-07-12 | — | — | US | disclosed |
| EP-0257433-A2 | Method for the preparation of quinoline-2,3-dicarboxylic acid | AMERICAN CYANAMID COMPANY (US) | 1988-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12202806-B2 | Eco-friendly materials and methods for renewable and sustainable applications in material chemistry | PPOX, GRHPR, HDHD5 | CYP1A2 894/4885TDP1 2372/4885CASP6 4264/4885 |
| US-20090093526-A1 | INHIBITION OF P38 KINASE USING SYMMETRICAL AND UNSYMMETRICAL DIPHENYL UREAS | MAP2K2, MAPK1, MAP2K1 | CYP1A2 1131/4885TDP1 1255/4885CASP6 656/4885 |
| US-20040102636-A1 | Inhibition of p38 kinase using symmetrical and unsymmetrical diphenyl ureas | MAP2K2, MAPK1, MAP2K1 | CYP1A2 1131/4885TDP1 1255/4885CASP6 656/4885 |
| US-20210163424-A1 | ECO-FRIENDLY MATERIALS AND METHODS FOR RENEWABLE AND SUSTAINABLE APPLICATIONS IN MATERIAL CHEMISTRY | PPOX, GRHPR, HDHD5 | CYP1A2 894/4885TDP1 2372/4885CASP6 4264/4885 |
| US-10919866-B2 | Eco-friendly materials and methods for renewable and sustainable applications in material chemistry | PPOX, GRHPR, HDHD5 | CYP1A2 894/4885TDP1 2372/4885CASP6 4264/4885 |
| US-20190047965-A1 | ECO-FRIENDLY MATERIALS AND METHODS FOR RENEWABLE AND SUSTAINABLE APPLICATIONS IN MATERIAL CHEMISTRY | PPOX, GRHPR, HDHD5 | CYP1A2 894/4885TDP1 2372/4885CASP6 4264/4885 |
| US-20080269265-A1 | Inhibition Of Raf Kinase Using Symmetrical And Unsymmetrical Substituted Diphenyl Ureas | BRAF, RAF1, MAP2K2 | CYP1A2 2365/4885TDP1 1568/4885CASP6 3040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.