SCHEMBL28110623

SCHEMBL28110623

O=C1C=CC(=O)N1Nc1ccc(Nc2ccccc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 2/20 0.61
ALDH1A1 P00352 8/20 0.52
ALOX12 P18054 5/20 0.52
HSD17B10 Q99714 3/20 0.52
TDP1 Q9NUW8 3/20 0.52
L3MBTL1 Q9Y468 3/20 0.52
TSHR P16473 2/20 0.52
ALOX15 P16050 1/20 0.52
PTGS1 P23219 1/20 0.52
SLC6A2 P23975 1/20 0.52
MAPK1 P28482 1/20 0.52
PTGS2 P35354 1/20 0.52
HTR2B P41595 1/20 0.52
CYP1A2 P05177 2/20 0.52
MAPT P10636 7/20 0.47
HPGD P15428 4/20 0.47
NPSR1 Q6W5P4 3/20 0.47
GAA P10253 3/20 0.47
CCR6 P51684 2/20 0.47
CACNA1B Q00975 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18677769 0.92 CYP1A2 (0.59) HSP90AA1ALDH1A1ALOX12HSD17B10TDP1
SCHEMBL87617 0.92 CYP1A2 (0.59) HSP90AA1ALDH1A1ALOX12HSD17B10TDP1
SCHEMBL27758211 0.79 MGLL (0.44) HSP90AA1ALDH1A1ALOX12TDP1CYP1A2
SCHEMBL27822379 0.78 MAPK13 (0.55) HSP90AA1ALDH1A1HSD17B10TDP1L3MBTL1
SCHEMBL26688275 0.77 FAAH (0.50) ALDH1A1ALOX12TDP1CYP1A2MAPT
SCHEMBL28075355 0.77 MEN1 (0.53) HSP90AA1ALDH1A1HSD17B10TDP1L3MBTL1
SCHEMBL571682 0.76 HSP90AA1 (1.00) HSP90AA1ALDH1A1ALOX12HSD17B10TDP1
SCHEMBL27683564 0.76 MGLL (0.51) HSP90AA1ALDH1A1ALOX12CYP1A2MAPT
SCHEMBL27845392 0.75 LMNA (0.49) HSP90AA1ALDH1A1ALOX12TDP1CYP1A2
SCHEMBL27438302 0.75 LMNA (0.51) HSP90AA1ALDH1A1ALOX12TDP1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106795381-A Erodible antifouling paint composition PPG涂料欧洲有限责任公司 2017-05-31 CN disclosed
CN-106133027-A Coating composition PPG涂料欧洲有限责任公司 2016-11-16 CN disclosed