Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1206383 | 0.83 | HDAC3 (0.47) | LMNAALDH1A1CNR1CNR2GAA | |
| SCHEMBL10332301 | 0.82 | CYP2C9 (0.40) | LMNAHTTL3MBTL1ALDH1A1CNR1 | |
| SCHEMBL27405464 | 0.81 | MAPT (0.52) | CNR1CNR2HDAC3HDAC4HDAC1 | |
| SCHEMBL28625693 | 0.81 | HDAC3 (0.63) | LMNACNR1CNR2SMN1; SMN2HDAC3 | |
| SCHEMBL10332432 | 0.81 | CYP2C9 (0.39) | LMNAHTTL3MBTL1ALDH1A1CNR1 | |
| SCHEMBL24571259 | 0.79 | KEAP1 (0.58) | HTTL3MBTL1SMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL10332431 | 0.79 | ALDH1A1 (0.36) | LMNAHTTL3MBTL1ALDH1A1CNR1 | |
| SCHEMBL4620848 | 0.78 | HTT (0.56) | LMNAHTTL3MBTL1ALDH1A1CNR1 | |
| SCHEMBL9473250 | 0.76 | CNR1 (0.54) | LMNAHTTL3MBTL1ALDH1A1CNR1 | |
| SCHEMBL2845025 | 0.75 | HDAC3 (0.61) | LMNAHTTL3MBTL1ALDH1A1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | disclosed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |