Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 3/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694866 | 0.91 | MAPK1 (0.55) | DRD3HRH3MAPK1RAB9AALDH1A1 | |
| SCHEMBL23089941 | 0.81 | SLC2A1 (0.44) | RAB9AKDM4EL3MBTL1SLC2A1 | |
| SCHEMBL29372017 | 0.81 | SLC2A1 (0.44) | RAB9AKDM4EL3MBTL1SLC2A1 | |
| SCHEMBL29371832 | 0.79 | SLC2A1 (0.41) | ALDH1A1L3MBTL1SLC2A1 | |
| SCHEMBL23089896 | 0.79 | SLC2A1 (0.41) | ALDH1A1L3MBTL1SLC2A1 | |
| SCHEMBL10693530 | 0.79 | TDP1 (0.58) | HRH3ALDH1A1HTR2AHTR7KDM4E | |
| SCHEMBL23089920 | 0.79 | CYP2A6 (0.40) | RAB9AALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL29368618 | 0.79 | CYP2A6 (0.40) | RAB9AALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL23089911 | 0.78 | SLC2A1 (0.43) | L3MBTL1SLC2A1 | |
| SCHEMBL23089963 | 0.78 | SLC2A1 (0.43) | L3MBTL1SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |