Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
| ▸ | HTR7 | P34969 | 2/20 | 0.56 |
| ▸ | HTR6 | P50406 | 2/20 | 0.56 |
| ▸ | ACP1 | P24666 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GCGR | P47871 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695028 | 0.94 | HRH3 (0.64) | TDP1ALDH1A1HRH3HTR2AHTR7 | |
| SCHEMBL10688459 | 0.94 | HRH3 (0.64) | TDP1ALDH1A1HRH3HTR2AHTR7 | |
| SCHEMBL10694180 | 0.89 | TDP1 (0.49) | TDP1ALDH1A1HRH3HTR2AHTR7 | |
| SCHEMBL10694866 | 0.87 | MAPK1 (0.55) | TDP1ALDH1A1HRH3KDM4E | |
| SCHEMBL10694755 | 0.82 | MEN1 (0.64) | TDP1ALDH1A1HRH3HTR2AHTR7 | |
| SCHEMBL10687788 | 0.82 | ALDH1A1 (0.53) | TDP1ALDH1A1CYP2D6KDM4ESMN1; SMN2 | |
| SCHEMBL10694843 | 0.81 | HRH3 (0.50) | TDP1HRH3HTR2AHTR7HTR6 | |
| SCHEMBL11169002 | 0.80 | POLB (0.60) | TDP1ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL10692945 | 0.79 | DRD3 (0.47) | ALDH1A1HRH3HTR2AHTR7KDM4E | |
| SCHEMBL11162957 | 0.78 | TSHR (0.58) | TDP1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |