Catechol

Catechol

SCHEMBL10692995

O=P(O)(O)S.O=P(O)(O)S.Oc1ccccc1O

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.59
CA2 P00918 4/20 0.59
KDM4E B2RXH2 4/20 0.59
HPGD P15428 4/20 0.59
CA4 P22748 3/20 0.59
SMN1; SMN2 Q16637 3/20 0.59
ALOX15 P16050 3/20 0.59
HSD17B10 Q99714 3/20 0.59
CYP3A4 P08684 2/20 0.59
CA5A P35218 2/20 0.59
HIF1A Q16665 2/20 0.59
CA12 O43570 2/20 0.59
CA14 Q9ULX7 2/20 0.59
MAPT P10636 2/20 0.59
EGFR P00533 2/20 0.59
LMNA P02545 2/20 0.59
FYN P06241 2/20 0.59
MMP9 P14780 2/20 0.59
RECQL P46063 2/20 0.59
TDP1 Q9NUW8 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Catechol SCHEMBL30489767 0.88 ALDH1A1 (0.67) ALDH1A1CA2KDM4EHPGDCA4
Catechol SCHEMBL28373127 0.88 ALDH1A1 (0.67) ALDH1A1CA2KDM4EHPGDCA4
Catechol SCHEMBL11752660 0.88 ALDH1A1 (0.67) ALDH1A1CA2KDM4EHPGDCA4
Catechol SCHEMBL9238063 0.88 ALDH1A1 (0.67) ALDH1A1CA2KDM4EHPGDCA4
Catechol SCHEMBL29655429 0.85 ALDH1A1 (0.62) ALDH1A1CA2KDM4EHPGDCA4
Catechol SCHEMBL28803682 0.85 ALDH1A1 (0.62) ALDH1A1CA2KDM4EHPGDCA4
Catechol SCHEMBL11748956 0.85 ALDH1A1 (0.62) ALDH1A1CA2KDM4EHPGDCA4
Catechol SCHEMBL10692999 0.82 ALDH1A1 (0.59) ALDH1A1CA2KDM4EHPGDCA4
Resorcinol SCHEMBL9772963 0.81 CYP3A4 (0.52) ALDH1A1CA2KDM4EHPGDCA4
Phenol SCHEMBL11544071 0.80 CA2 (0.61) CA2CA4ALOX15CYP3A4CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4729848-A OIL ADDITIVES CHEVRON RESEARCH COMPANY (US) 1988-03-08 US disclosed
US-4668409-A Lubricating oil compositions containing overbased calcium sulfonates and metal salts of alkyl catechol dithiophosphoric acid CHEVRON RESEARCH COMPANY (US) 1987-05-26 US disclosed