Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 9/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1369193 | 0.92 | ALDH1A1 (0.80) | ALDH1A1HPGDCYP3A4HSD17B10TDP1 | |
| SCHEMBL3176397 | 0.90 | ALDH1A1 (0.82) | ALDH1A1HPGDCYP3A4HSD17B10TDP1 | |
| SCHEMBL10689289 | 0.90 | ALDH1A1 (0.82) | ALDH1A1HPGDCYP3A4HSD17B10TDP1 | |
| SCHEMBL8930953 | 0.88 | ALDH1A1 (0.67) | ALDH1A1HPGDCYP3A4HSD17B10TDP1 | |
| SCHEMBL8322552 | 0.88 | ALDH1A1 (0.78) | ALDH1A1HPGDCYP3A4HSD17B10TDP1 | |
| SCHEMBL4851834 | 0.87 | ALDH1A1 (0.65) | ALDH1A1HPGDCYP3A4HSD17B10TDP1 | |
| SCHEMBL536831 | 0.87 | ALDH1A1 (0.80) | ALDH1A1HPGDCYP3A4HSD17B10TDP1 | |
| SCHEMBL1074866 | 0.85 | ALDH1A1 (0.68) | ALDH1A1HPGDCYP3A4HSD17B10TDP1 | |
| SCHEMBL9319662 | 0.85 | ALDH1A1 (0.69) | ALDH1A1HPGDCYP3A4HSD17B10TDP1 | |
| SCHEMBL9320001 | 0.85 | ALDH1A1 (0.69) | ALDH1A1HPGDCYP3A4HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4732991-A | Substituted phthalides | HILTON DAVIS CHEMICAL CO. (US) | 1988-03-22 | — | — | US | disclosed |
| US-4595768-A | 3-(substituted phenyl)phthalides | THE HILTON-DAVIS CHEMICAL CO. (US) | 1986-06-17 | — | — | US | disclosed |