Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11062281 | 0.93 | ABCB1 (0.44) | ALDH1A1ABCB1KDM4EUSP2GAA | |
| SCHEMBL10692102 | 0.86 | LMNA (0.44) | ALDH1A1LMNAL3MBTL1MAOBNPC1 | |
| SCHEMBL339072 | 0.86 | ALDH1A1 (0.47) | ALDH1A1KDM4EGAAHSD17B10MAOB | |
| SCHEMBL11073315 | 0.84 | ALDH1A1 (0.45) | ALDH1A1KDM4EUSP2GAAHSD17B10 | |
| SCHEMBL1653589 | 0.84 | ALDH1A1 (0.41) | ALDH1A1KDM4EGAAHSD17B10L3MBTL1 | |
| SCHEMBL10692371 | 0.83 | PDE4A (0.45) | ALDH1A1KDM4EGAALMNANPSR1 | |
| SCHEMBL10680094 | 0.82 | ALDH1A1 (0.44) | ALDH1A1KDM4EGAAHSD17B10MAOB | |
| SCHEMBL11281281 | 0.82 | ALDH1A1 (0.44) | ALDH1A1KDM4EGAAHSD17B10LMNA | |
| SCHEMBL11063311 | 0.82 | ALDH1A1 (0.58) | ALDH1A1KDM4EGAAHSD17B10LMNA | |
| SCHEMBL11070301 | 0.81 | ATM (0.48) | ALDH1A1ABCB1KDM4EUSP2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4595768-A | 3-(substituted phenyl)phthalides | THE HILTON-DAVIS CHEMICAL CO. (US) | 1986-06-17 | — | — | US | claimed |
| US-4732991-A | Substituted phthalides | HILTON DAVIS CHEMICAL CO. (US) | 1988-03-22 | — | — | US | disclosed |
| US-4595768-A | 3-(substituted phenyl)phthalides | THE HILTON-DAVIS CHEMICAL CO. (US) | 1986-06-17 | — | — | US | disclosed |