Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 3/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 3/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL822754 | 0.90 | MEN1 (0.54) | METAP1GAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15483667 | 0.88 | METAP1 (0.63) | METAP1GAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL25499549 | 0.88 | METAP1 (0.70) | METAP1GAASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL1609651 | 0.86 | METAP1 (0.71) | METAP1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6056920 | 0.84 | METAP1 (0.69) | METAP1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10623445 | 0.83 | ALDH1A1 (0.64) | METAP1GAAKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9971917 | 0.82 | ELANE (0.62) | ALDH1A1HPGDACHEKDM4EMAOB | |
| SCHEMBL22604000 | 0.82 | ELANE (0.62) | ALDH1A1HPGDACHEKDM4EMAOB | |
| SCHEMBL15869812 | 0.82 | ELANE (0.57) | METAP1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL15869786 | 0.82 | METAP1 (0.54) | METAP1GAAMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |