Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 3/20 | 0.54 |
| ▸ | DRD2 | P14416 | 4/20 | 0.51 |
| ▸ | DRD1 | P21728 | 4/20 | 0.51 |
| ▸ | DRD5 | P21918 | 4/20 | 0.51 |
| ▸ | DRD3 | P35462 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15483667 | 0.91 | METAP1 (0.63) | METAP1DRD2DRD1DRD5DRD3 | |
| SCHEMBL4581239 | 0.90 | METAP1 (0.63) | METAP1DRD2DRD1DRD5DRD3 | |
| SCHEMBL30777630 | 0.90 | METAP1 (0.63) | METAP1DRD2DRD1DRD5DRD3 | |
| SCHEMBL15869785 | 0.89 | MPO (0.51) | METAP1ALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL822754 | 0.85 | MEN1 (0.54) | METAP1DRD2DRD1DRD5DRD3 | |
| SCHEMBL29633547 | 0.83 | METAP1 (0.57) | METAP1ALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL4897556 | 0.83 | METAP1 (0.57) | METAP1ALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL19850967 | 0.83 | METAP1 (0.47) | METAP1DRD2DRD1DRD5DRD3 | |
| SCHEMBL10693161 | 0.82 | METAP1 (0.64) | METAP1DRD2DRD1DRD5DRD3 | |
| SCHEMBL2914928 | 0.81 | DRD1 (0.58) | METAP1DRD2DRD1DRD5DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9366906-B2 | Photoreactive compounds | ROLIC AG (CH) | 2016-06-14 | — | — | US | disclosed |
| US-20140192305-A1 | PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2014-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140192305-A1 | PHOTOREACTIVE COMPOUNDS | PCNA, CRY1, CRY2 | METAP1 2858/4885DRD2 1118/4885DRD1 898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.