Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL220343 | 0.73 | ALDH1A1 (0.50) | MAPTALDH1A1L3MBTL1HIF1AKDM4E | |
| SCHEMBL7383358 | 0.63 | GAA (0.41) | MAPTALDH1A1L3MBTL1GAATSHR | |
| SCHEMBL13341066 | 0.62 | MAPT (0.36) | MAPTALDH1A1CYP1A2CYP2C19KDM4E | |
| SCHEMBL5915582 | 0.62 | MAPT (0.61) | MAPTALDH1A1L3MBTL1HIF1AKDM4E | |
| SCHEMBL23336992 | 0.60 | HDAC3 (0.35) | MAPTL3MBTL1KDM4EGAAGLA | |
| SCHEMBL1257489 | 0.60 | ALDH1A1 (0.53) | ALDH1A1CYP1A2GAANPSR1TSHR | |
| SCHEMBL27879862 | 0.60 | ALDH1A1 (0.53) | ALDH1A1CYP1A2GAANPSR1TSHR | |
| SCHEMBL15460379 | 0.60 | MAPT (0.43) | MAPTALDH1A1CYP1A2CYP2C19KDM4E | |
| SCHEMBL7376669 | 0.60 | GAA (0.57) | MAPTALDH1A1L3MBTL1KDM4EGAA | |
| SCHEMBL10677017 | 0.60 | HTT (0.48) | MAPTALDH1A1CYP1A2KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4762830-A | 5-(azolyloxyphenylcarbamoyl)barbituric acid derivatives as anthelmintics | CIBA-GEIGY CORPORATION (US) | 1988-08-09 | — | — | US | disclosed |