Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24757599 | 0.88 | TYMS (0.53) | TYMSMEN1KMT2APOLBUSP2 | |
| SCHEMBL17133796 | 0.85 | TYMS (0.50) | TYMSMEN1KMT2APOLBUSP2 | |
| SCHEMBL31365971 | 0.85 | TYMS (0.50) | TYMSMEN1KMT2APOLBUSP2 | |
| SCHEMBL10490096 | 0.82 | PABPC1 (0.50) | MEN1KMT2APOLBUSP2KDM4E | |
| SCHEMBL15119610 | 0.80 | TYMS (0.45) | TYMSMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL20869689 | 0.80 | MEN1 (0.59) | MEN1KMT2APOLBUSP2KDM4E | |
| SCHEMBL10267341 | 0.80 | TYMS (0.70) | TYMSMEN1KMT2APOLBUSP2 | |
| SCHEMBL6984126 | 0.77 | MAPT (0.62) | TYMSMEN1KMT2APOLBUSP2 | |
| SCHEMBL11171228 | 0.76 | KMT2A (0.53) | TYMSMEN1KMT2APOLBUSP2 | |
| SCHEMBL13495361 | 0.75 | PRMT1 (0.48) | MEN1KMT2APOLBUSP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4782064-A | THROMBOXANE SYNTHETASE INHIBITORS | AMERICAN CYANAMID CO. (US) | 1988-11-01 | — | — | US | disclosed |