SCHEMBL10693276

SCHEMBL10693276

O=C(O)c1cc([N+](=O)[O-])ccc1C(=O)c1ccc(N2CCCC2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 8/20 0.62
SMN1; SMN2 Q16637 7/20 0.62
MAPT P10636 7/20 0.62
HTT P42858 3/20 0.62
POLB P06746 2/20 0.62
ALDH1A1 P00352 11/20 0.61
PAX8 Q06710 3/20 0.59
CYP1A2 P05177 1/20 0.59
CYP3A4 P08684 1/20 0.59
CYP2C9 P11712 1/20 0.59
CYP2C19 P33261 1/20 0.59
KDM4E B2RXH2 2/20 0.53
CTSL P07711 1/20 0.52
CTSB P07858 1/20 0.52
RAB9A P51151 3/20 0.51
NPC1 O15118 2/20 0.51
RECQL P46063 1/20 0.51
TP53 P04637 1/20 0.50
HPGD P15428 1/20 0.50
ALOX15 P16050 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10690606 0.95 LMNA (0.62) LMNASMN1; SMN2MAPTHTTPOLB
SCHEMBL10692709 0.84 ALDH1A1 (0.61) LMNASMN1; SMN2MAPTHTTPOLB
SCHEMBL11010668 0.80 LMNA (0.60) LMNASMN1; SMN2MAPTHTTPOLB
SCHEMBL10691055 0.79 SERPINE1 (0.65) LMNASMN1; SMN2MAPTHTTALDH1A1
SCHEMBL27660357 0.78 SRD5A2 (0.64) LMNASMN1; SMN2MAPTHTTPOLB
SCHEMBL27847447 0.78 MAPT (0.69) LMNASMN1; SMN2MAPTHTTPOLB
SCHEMBL18113433 0.77 ALDH1A1 (0.76) LMNASMN1; SMN2MAPTHTTPOLB
SCHEMBL10502203 0.77 ALDH1A1 (0.97) LMNASMN1; SMN2MAPTHTTPOLB
SCHEMBL9416202 0.77 ALDH1A1 (0.73) LMNASMN1; SMN2MAPTPOLBALDH1A1
SCHEMBL5051298 0.77 SRD5A2 (0.67) LMNAMAPTPOLBALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4748148-A Recording system utilizing phthalide derivatives as colorless chromogenic material NEW OJI PAPER CO., LTD. (JP) 1988-05-31 US disclosed
US-4641160-A Recording system utilizing phthalide derivatives as colorless chromogenic material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1987-02-03 US disclosed
EP-0127203-A1 New phthalide derivatives, process for preparing the same and recording system utilizing the same as colourless chromogenic material KANZAKI PAPER MANUFACTURING CO., LTD (JP) 1984-12-05 EP disclosed
EP-0062544-A1 New phthalide derivatives, process for preparing the same and recording system utilizing the same as colourless chromogenic material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1982-10-13 EP disclosed