Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | CA6 | P23280 | 1/20 | 0.58 |
| ▸ | CA5A | P35218 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3909923 | 0.91 | SMN1; SMN2 (0.65) | CA12CA1CA2CA4CA6 | |
| SCHEMBL14419604 | 0.85 | POLB (0.56) | POLBSMN1; SMN2HTTLMNAALDH1A1 | |
| SCHEMBL11137915 | 0.85 | POLB (0.56) | POLBSMN1; SMN2HTTLMNAALDH1A1 | |
| SCHEMBL10693029 | 0.84 | SMN1; SMN2 (0.53) | CA12CA1CA2CA4CA6 | |
| SCHEMBL939122 | 0.84 | POLB (0.63) | POLBSMN1; SMN2HTTLMNAALDH1A1 | |
| SCHEMBL7212214 | 0.84 | SMN1; SMN2 (0.58) | POLBSMN1; SMN2HTTLMNAALDH1A1 | |
| SCHEMBL10693083 | 0.81 | CA1 (0.63) | CA12CA1CA2CA4CA6 | |
| SCHEMBL10695843 | 0.81 | TSHR (0.54) | CA1CA2CA9POLBSMN1; SMN2 | |
| SCHEMBL10693591 | 0.80 | ALDH1A1 (0.60) | CA12CA1CA2CA4CA6 | |
| SCHEMBL10688819 | 0.79 | CA2 (0.66) | CA12CA1CA2CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4754024-A | Fibre-reactive azo dyes containing vinylsulfonyl or analogous groups | CIBA-GEIGY CORPORATION | 1988-06-28 | — | — | US | disclosed |