Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12841481 | 0.78 | MAPT (0.72) | MAPTCYP19A1POLBPPARGCYP1A2 | |
| SCHEMBL11181063 | 0.76 | MAPT (0.65) | MAPTCYP19A1CYP26A1CYP1A2CYP3A4 | |
| SCHEMBL28384165 | 0.76 | MAPT (0.44) | MAPTCYP19A1HPGDPPARAKDM4E | |
| SCHEMBL10838717 | 0.75 | CYP19A1 (0.49) | MAPTCYP19A1POLBHPGDCYP26A1 | |
| SCHEMBL10928863 | 0.75 | CYP3A4 (0.54) | MAPTCYP19A1POLBCYP26A1CYP1A2 | |
| SCHEMBL10568398 | 0.74 | MAPT (0.62) | MAPTCYP26A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10664398 | 0.72 | MAPT (0.60) | MAPTCYP19A1PPARGCYP26A1CYP1A2 | |
| SCHEMBL10664395 | 0.72 | MAPT (0.60) | MAPTCYP19A1PPARGCYP26A1CYP1A2 | |
| SCHEMBL10876276 | 0.72 | CYP3A4 (0.46) | MAPTCYP19A1POLBCYP3A4ALDH1A1 | |
| SCHEMBL5440264 | 0.72 | MAPT (0.49) | MAPTCYP19A1PPARGCYP26A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4743291-A | Herbicidal aryl triazolinones | FMC CORPORATION (US) | 1988-05-10 | — | — | US | disclosed |