Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694864 | 0.90 | AVPR1A (0.42) | MDM2TP53RECQLAVPR1A | |
| SCHEMBL9228271 | 0.84 | KMT2A (0.36) | MDM2TP53NPSR1L3MBTL1KMT2A | |
| SCHEMBL9228267 | 0.84 | KMT2A (0.36) | MDM2TP53NPSR1L3MBTL1KMT2A | |
| SCHEMBL9222237 | 0.75 | AVPR1A (0.39) | MDM2TP53KMT2AALDH1A1NPC1 | |
| SCHEMBL9222234 | 0.75 | AVPR1A (0.39) | MDM2TP53KMT2AALDH1A1NPC1 | |
| SCHEMBL9219312 | 0.70 | AVPR1A (0.44) | CYP2D6CYP2C9CYP2C19RAB9AAVPR1A | |
| SCHEMBL9219306 | 0.70 | AVPR1A (0.44) | CYP2D6CYP2C9CYP2C19RAB9AAVPR1A | |
| SCHEMBL22672484 | 0.64 | TSHR (0.34) | L3MBTL1KMT2AALDH1A1GAACYP2C19 | |
| SCHEMBL24064546 | 0.63 | TSHR (0.35) | L3MBTL1KMT2AALDH1A1GAACYP2C19 | |
| SCHEMBL10670704 | 0.63 | TP53 (0.39) | TP53NPSR1L3MBTL1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282895-A2 | 2-oxa-isocephem compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-09-21 | — | — | EP | disclosed |