Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 5/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693428 | 0.90 | MDM2 (0.34) | AVPR1ARECQLTP53MDM2 | |
| SCHEMBL9222234 | 0.86 | AVPR1A (0.39) | AVPR1AELANEGPBAR1TP53MDM2 | |
| SCHEMBL9222237 | 0.86 | AVPR1A (0.39) | AVPR1AELANEGPBAR1TP53MDM2 | |
| SCHEMBL9219306 | 0.82 | AVPR1A (0.44) | AVPR1AELANE | |
| SCHEMBL9219312 | 0.82 | AVPR1A (0.44) | AVPR1AELANE | |
| SCHEMBL9228267 | 0.76 | KMT2A (0.36) | TP53MDM2 | |
| SCHEMBL9228271 | 0.76 | KMT2A (0.36) | TP53MDM2 | |
| SCHEMBL8569288 | 0.69 | MAPK1 (0.45) | ELANE | |
| SCHEMBL9225470 | 0.68 | AVPR1A (0.47) | AVPR1AELANE | |
| SCHEMBL9225461 | 0.68 | AVPR1A (0.47) | AVPR1AELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282895-A2 | 2-oxa-isocephem compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-09-21 | — | — | EP | disclosed |