Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9228267 | 1.00 | KMT2A (0.36) | KMT2AALDH1A1CYP1A2CYP2C19GAA | |
| SCHEMBL9222237 | 0.91 | AVPR1A (0.39) | KMT2AALDH1A1CYP1A2CYP2C19MAPT | |
| SCHEMBL9222234 | 0.91 | AVPR1A (0.39) | KMT2AALDH1A1CYP1A2CYP2C19MAPT | |
| SCHEMBL10693428 | 0.84 | MDM2 (0.34) | KMT2AALDH1A1CYP1A2CYP2C19GAA | |
| SCHEMBL9219312 | 0.76 | AVPR1A (0.44) | CYP2C19CYP2D6CYP2C9RAB9A | |
| SCHEMBL9219306 | 0.76 | AVPR1A (0.44) | CYP2C19CYP2D6CYP2C9RAB9A | |
| SCHEMBL10694864 | 0.76 | AVPR1A (0.42) | MDM2TP53 | |
| SCHEMBL10670704 | 0.63 | TP53 (0.39) | KMT2AALDH1A1MAPTTP53POLB | |
| SCHEMBL29647573 | 0.62 | CYP2D6 (0.47) | KMT2AALDH1A1CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL10676205 | 0.62 | AVPR1A (0.52) | KMT2AALDH1A1CYP2C19CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282895-B1 | 2-oxa-isocephem compounds, compositions containing same and processes for preparing same | OTSUKA PHARMA CO LTD (JP) | 1995-06-07 | — | — | EP | disclosed |
| US-5037976-A | Antimicrobial Agent | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-08-06 | — | — | US | disclosed |
| US-4898859-A | 2-Oxa-isocephem compounds and compositions containing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-06 | — | — | US | disclosed |