Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691520 | 0.86 | ALDH1A1 (0.39) | MAPTTDP1ALDH1A1KDM4EHPGD | |
| SCHEMBL27883374 | 0.85 | MAPT (0.57) | MAPTTDP1ALDH1A1LCKFYN | |
| SCHEMBL9353417 | 0.85 | MAPT (0.61) | MAPTTDP1ALDH1A1LCKFYN | |
| SCHEMBL27840740 | 0.79 | ALDH1A1 (0.62) | MAPTTDP1ALDH1A1KDM4EHPGD | |
| SCHEMBL6648374 | 0.78 | MAPT (0.55) | MAPTTDP1ALDH1A1LCKFYN | |
| SCHEMBL28112142 | 0.78 | HTT (0.51) | MAPTTDP1ALDH1A1KDM4EHPGD | |
| SCHEMBL27955903 | 0.77 | ALDH1A1 (0.60) | MAPTTDP1ALDH1A1KDM4EHPGD | |
| SCHEMBL10163156 | 0.75 | CA12 (0.43) | MAPTTDP1ALDH1A1LCKFYN | |
| SCHEMBL17339024 | 0.75 | MAPT (0.51) | MAPTTDP1ALDH1A1LCKFYN | |
| SCHEMBL2337418 | 0.75 | MAPT (0.66) | MAPTTDP1ALDH1A1LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4764525-A | N-1H-tetrazol-5-ylbenzamides having use as antiallergy and antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1988-08-16 | — | — | US | disclosed |