Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 2/20 | 0.50 |
| ▸ | NAAA | Q02083 | 2/20 | 0.49 |
| ▸ | TLR2 | O60603 | 5/20 | 0.48 |
| ▸ | KLK7 | P49862 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23397628 | 0.85 | LMNA (0.51) | ASAH1NAAATLR2ALDH1A1ACER2 | |
| SCHEMBL18206788 | 0.85 | LMNA (0.51) | ASAH1NAAATLR2ALDH1A1ACER2 | |
| SCHEMBL10694432 | 0.82 | LMNA (0.49) | ASAH1NAAATLR2ALDH1A1ACER2 | |
| SCHEMBL19107048 | 0.80 | LMNA (0.46) | ASAH1TLR2ALDH1A1ACER2LMNA | |
| SCHEMBL10694396 | 0.80 | KLK7 (0.60) | KLK7PKM | |
| SCHEMBL4214175 | 0.79 | LMNA (0.54) | ASAH1NAAATLR2ALDH1A1ACER2 | |
| SCHEMBL966243 | 0.79 | LMNA (0.54) | ASAH1NAAATLR2ALDH1A1ACER2 | |
| SCHEMBL966036 | 0.79 | LMNA (0.54) | ASAH1NAAATLR2ALDH1A1ACER2 | |
| SCHEMBL964635 | 0.79 | LMNA (0.54) | ASAH1NAAATLR2ALDH1A1ACER2 | |
| SCHEMBL4208878 | 0.79 | LMNA (0.54) | ASAH1NAAATLR2ALDH1A1ACER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |