Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.47 |
| ▸ | TLR2 | O60603 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 2/20 | 0.43 |
| ▸ | CERT1 | Q9Y5P4 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11114166 | 0.90 | KDM4E (0.53) | LMNAMAPTALDH1A1KDM4E | |
| SCHEMBL18206788 | 0.88 | LMNA (0.51) | LMNAASAH1TLR2MAPTMAPK1 | |
| SCHEMBL30183305 | 0.88 | L3MBTL1 (0.49) | LMNAMAPTALDH1A1CES2CES1 | |
| SCHEMBL19107048 | 0.83 | LMNA (0.46) | LMNAASAH1TLR2MAPTMAPK1 | |
| SCHEMBL10693617 | 0.82 | ASAH1 (0.50) | LMNAASAH1TLR2MAPTMAPK1 | |
| SCHEMBL966243 | 0.82 | LMNA (0.54) | LMNAASAH1TLR2MAPTMAPK1 | |
| SCHEMBL964635 | 0.82 | LMNA (0.54) | LMNAASAH1TLR2MAPTMAPK1 | |
| SCHEMBL966036 | 0.82 | LMNA (0.54) | LMNAASAH1TLR2MAPTMAPK1 | |
| SCHEMBL966479 | 0.82 | LMNA (0.54) | LMNAASAH1TLR2MAPTMAPK1 | |
| SCHEMBL963663 | 0.82 | LMNA (0.54) | LMNAASAH1TLR2MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | disclosed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |