SCHEMBL10693711

SCHEMBL10693711

C=CCc1ccc(Cc2ccc(CC=C)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.56
CYP3A4 P08684 5/20 0.56
TSHR P16473 3/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
TP53 P04637 1/20 0.56
ALOX15 P16050 1/20 0.56
ALOX12 P18054 1/20 0.56
XDH P47989 1/20 0.50
MAPT P10636 3/20 0.48
GABRA1 P14867 3/20 0.48
GABRB2 P47870 3/20 0.48
CNR2 P34972 3/20 0.48
PPARG P37231 2/20 0.48
PPARD Q03181 2/20 0.48
MEN1 O00255 2/20 0.48
GAA P10253 2/20 0.48
CNR1 P21554 2/20 0.48
KMT2A Q03164 2/20 0.48
KDM4E B2RXH2 1/20 0.48
ALDH2 P05091 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL173301 0.91 ALDH1A1 (0.64) ALDH1A1CYP3A4TSHRSMN1; SMN2TP53
Bromide SCHEMBL8645583 0.88 ALDH1A1 (0.61) ALDH1A1CYP3A4TSHRSMN1; SMN2TP53
Phosphine SCHEMBL28908227 0.88 ALDH1A1 (0.61) ALDH1A1CYP3A4TSHRSMN1; SMN2TP53
Water SCHEMBL29179560 0.88 ALDH1A1 (0.61) ALDH1A1CYP3A4TSHRSMN1; SMN2TP53
Hydrogen Peroxide SCHEMBL5496256 0.85 ALDH1A1 (0.58) ALDH1A1CYP3A4TSHRSMN1; SMN2TP53
Hydrogen Peroxide SCHEMBL7816450 0.85 ALDH1A1 (0.58) ALDH1A1CYP3A4TSHRSMN1; SMN2TP53
SCHEMBL6324230 0.82 ALDH1A1 (0.47) ALDH1A1CYP3A4TSHRSMN1; SMN2TP53
SCHEMBL20045130 0.82 LOXL2 (0.48) ALDH1A1CYP3A4TSHRSMN1; SMN2TP53
SCHEMBL584333 0.82 ALDH1A1 (0.56) ALDH1A1CYP3A4TSHRSMN1; SMN2TP53
SCHEMBL6284374 0.82 ALDH1A1 (0.56) ALDH1A1CYP3A4TSHRSMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106916400-B Resin composition, adhesive film, and method for producing coreless substrate 味之素株式会社 2022-07-05 CN disclosed
CN-106256853-B Resin composition for mold underfill 味之素株式会社 2021-04-06 CN disclosed
EP-0272425-A2 Resin blends exhibiting improved impact properties GENERAL ELECTRIC COMPANY (US) 1988-06-29 EP disclosed
EP-0269861-A2 Impact modified aromatic carbonate compositions GENERAL ELECTRIC COMPANY (US) 1988-06-08 EP disclosed