Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 2/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692715 | 0.88 | L3MBTL1 (0.40) | HTR1BCHEK1CYP2A6MCL1SLC6A2 | |
| SCHEMBL10695347 | 0.88 | HTR1B (0.47) | HTR1BCHEK1HTR2ACYP2A6MCL1 | |
| SCHEMBL10690407 | 0.88 | HTR1B (0.56) | HTR1BHTR2AL3MBTL1MAOASSTR2 | |
| SCHEMBL10692059 | 0.86 | HTR1B (0.54) | HTR1BHTR2ASSTR2SSTR4HDAC3 | |
| SCHEMBL10695724 | 0.86 | HTR1B (0.54) | HTR1BHTR2ASSTR2SSTR4HDAC3 | |
| SCHEMBL10688833 | 0.86 | HTR1B (0.54) | HTR1BHTR2ASSTR2SSTR4HDAC3 | |
| SCHEMBL10692231 | 0.86 | HTR1B (0.54) | HTR1BHTR2ASSTR2SSTR4HDAC3 | |
| SCHEMBL10693528 | 0.86 | HTR1B (0.54) | HTR1BHTR2ASSTR2SSTR4HDAC3 | |
| SCHEMBL10692940 | 0.86 | HTR1B (0.54) | HTR1BHTR2ASSTR2SSTR4HDAC3 | |
| SCHEMBL10694132 | 0.86 | HTR1B (0.54) | HTR1BHTR2ASSTR2SSTR4HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |