Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | FERMT2 | Q96AC1 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 2/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | BAD | Q92934 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691905 | 0.89 | L3MBTL1 (0.41) | HTR1BHTR2ACYP2A6L3MBTL1BCL2 | |
| SCHEMBL10693771 | 0.88 | HTR1B (0.45) | HTR1BHTR2ACYP2A6CHEK1FERMT2 | |
| SCHEMBL10691171 | 0.87 | HTR1B (0.59) | HTR1BHTR2AL3MBTL1GPR84 | |
| SCHEMBL10694803 | 0.85 | PARP1 (0.42) | HTR1BCHEK1FERMT2 | |
| SCHEMBL10690407 | 0.84 | HTR1B (0.56) | HTR1BHTR2AL3MBTL1GPR84 | |
| SCHEMBL10692940 | 0.82 | HTR1B (0.54) | HTR1BHTR2AGPR84 | |
| SCHEMBL10688833 | 0.82 | HTR1B (0.54) | HTR1BHTR2AGPR84 | |
| SCHEMBL10692231 | 0.82 | HTR1B (0.54) | HTR1BHTR2AGPR84 | |
| SCHEMBL10693528 | 0.82 | HTR1B (0.54) | HTR1BHTR2AGPR84 | |
| SCHEMBL10695724 | 0.82 | HTR1B (0.54) | HTR1BHTR2AGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |