Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690647 | 0.88 | CHRM5 (0.56) | ALDH1A1L3MBTL1MAPTKDM4ECHRM5 | |
| SCHEMBL10693518 | 0.84 | RNF4 (0.58) | ALDH1A1MEN1KMT2AMAPK1CHRM1 | |
| SCHEMBL9676729 | 0.83 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL10694263 | 0.81 | CNR2 (0.54) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL10693054 | 0.80 | NPC1 (0.52) | LMNAALDH1A1SMN1; SMN2NPC1HTT | |
| SCHEMBL10689083 | 0.80 | HTT (0.49) | LMNAALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL23201983 | 0.76 | MAPT (0.78) | LMNATSHRALDH1A1L3MBTL1MEN1 | |
| SCHEMBL29937922 | 0.76 | MAPT (0.78) | LMNATSHRALDH1A1L3MBTL1MEN1 | |
| SCHEMBL27572248 | 0.74 | CHRM5 (0.62) | ALDH1A1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL10694993 | 0.74 | CHRM5 (0.54) | MEN1KMT2ANPSR1CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |